Posted by: christopher



Glucosamine can be a wonder drug for dog arthritis – there are many fantastic stories of safe and effective improvements in mobility and quality of life. Yet whilst there are many happy stories there are also some disappointments – and many of these disappointments can be traced back to using low doses of low quality glucosamine products. You want to get glucosamine for dogs right the first time – good quality drugs at the correct dose! There are a few tricks to getting the glucosamine dose right which I will explain below.

Are You Giving the Right Type of Glucosamine?

There are in fact 5 forms of glucosamine, the main difference being Glucosamine Sulfate versus Glucosamine Hydrochloride (HCl) and also differences in the origin of the Glucosamine HCl (vegetable versus shellfish). Glucosamine hydrochloride (glucosamine HCl) seems to work best and whilst there are some arguments to say the vegetable form of Glucosamine HCl works better than the shellfish form, this has yet to be proven. It does appear that Glucosamine HCl works even better if combined with low molecular weight chondroitin sulfate so I think this is a more important point.

Are You Giving the Right Dose of Glucosamine HCl?

These drugs are safe so it is hard to give too high a dose. Yet despite their safety many dogs receive very low doses that really won’t be effective. Why? Price. Whichever way you look at it these drugs can be expensive, especially if you have a big dog. So think of it this way… if you give a low dose you will likely hit one of these situations:

  • The glucosamine has not worked because the dose was too low


  • The glucosamine has not worked because it simply doesn’t work in every dog.


So how do you pick these two apart? You need to try all over again on a higher dose, all the while feeling a little sheepish at your false economy. My advice is to try good products at a good dose and back down from there.  Drugs like Dasuquin and Cosequin are the gold standard – if they do not work, nothing will. Try them first and if they help then flip over to a maintenance dose after 4-6 weeks. The price becomes much more tolerable as you give these products every 2nd day. The ingredients of Dasuquin have been tabled below – they should give you a guide as to how much of each ingredient to give. [table id=2 /]
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Comments (15)

  1. Posted by: brandon March 24, 2013, 9:38 AM

    besides the Cosequin DS Plus MSM, i just started my dog on the Canine Flex Support. in addition to the G & C, it also contains Vitamin E & C. other ingredients are honey, ginger root, bovine liver, maltodextrin, gum acacia, turmeric extract, and calcium stearate.

    my dog is 15-1/2 yrs old & still puts on a mile or more on his paws daily.

  2. Posted by: Mandy March 2, 2013, 3:08 PM

    I have a 100lb lab. I bought Nature Made Triple Flex…2 capsules per serving which include Glucosamine 1500mg, Chondroitin 800mg, MSM 750mg. Is this a good choice and do I give her the full serving?

    1. Posted by: christopher March 5, 2013, 5:38 AM

      Mandy, I prefer glycanaid as you would know if you read my blog. But this looks ok. The MSM dose could be doubled and you might want to consider some hyaluronic acid which comes in liquid form.

      Dr. Chris

    2. Posted by: Denise Johnson June 5, 2013, 5:41 AM

      Hi Mandy, I was wondering how the Costco Triple Flex was working for your Lab and if you still give 2 pills per day? I have a 5 year dog that Vet had on Canine medicine but I seen others say they use Nature Made Triple Flex which is 1/3 of the price for the medicine the Vet has my lab on. I just was concern if human med was ok and the dosage and most important, does it work.

  3. Posted by: Kurt December 6, 2012, 3:13 PM

    I have a 3-year-old Husky/lab cross. The anterior cruciate ligament in her back leg has been operated on. For her arthritis, my vet suggested Gluco but he said the only brand we can give dogs is Costco’s Kirkland brand, and 1000mg. Yet I can’t find it in 1000mg.. only 1500mg. My dog is around 60 lbs. Does it have to be 1000mg? and explain to me MSM and Chondroitin please! I’m new to this! thanks!

    1. Posted by: christopher December 7, 2012, 10:17 PM

      Hi Kurt,

      There are plenty of different types of Glucosamine. It is important to remember that it is not just the glucosamine you are interested in but also chondroitin, MSM and hyaluronic acid.

      The dose is approximatelt 600mg of glucosamine but up to 1000mg is fine.

      I suggest the doggy varieties first as there are differences in formulation. Once you are getting the results you can possibly switch to the cheaper human brands but make sure they are still doing the job.

      The best of the doggy brands is called Glycanaid, which comes with my very cool book on dog arthritis for free.

      Glycanaid + Book ‘Modern Dog Arthritis Treatment’

      Hope that helps :)

      Dr. Chris

  4. Posted by: ica December 4, 2012, 5:00 PM

    is human glucosamine good for dogs?

    1. Posted by: christopher December 7, 2012, 10:19 PM

      Hi ica,

      Glucosamine for humans is good for dogs. The dose is about 22mg/kg

      Having said that there are differences in the formulations and using glucosamine by itself is not my recommendation. I also suggest chondroitin, MSM and hyaluronic acid.

      The doggy formulation is best to start then when you are getting good results you can switch to a good quality human brand if they are cheaper. My suggested starter supplement is Glycanaid which you can get here with my book for no extra cost.

      Glycanaid + Book ‘Modern Dog Arthritis Treatment’

      Hope that helps :)

      Dr. Chris

  5. Posted by: kelly September 1, 2012, 2:43 PM

    I was wondering – I have a 12 yaer old that I have been tryign to change over to taking the glucosimine now that they vet has called her a senior this past month. I also will be getting a 10 week old puppy. I was wondering if some how the puppy got some of her food from her dish with this med ( she will not take pills ) will it hurt him?

    1. Posted by: christopher September 5, 2012, 6:30 AM

      Hi Kelly, Glucosamine is super safe. Even a full adult dog dose would likely only cause some diarrhoea. Go for it!

      Let me know if you need some help with the supplements.

  6. Posted by: Courtney August 1, 2012, 10:30 PM

    Using this chart against your calculator, I’m finding some real differences on dosage. I have a 10 lb and 50 lb dog. If you calculate the 10 lb weight in the calculator for both glucosamine and MSM, you get an average recommended dose of 100 mg. Above it says 300 mg for glucosamine and 200 mg for MSM. For my 50 lb dog, the calculator says 500 mg for glucosamine and MSM. The chart above says approx 1200 mg for glucosamine and 800 mg for MSM. Which recommended dosage should I go by? I only looked at those 2 ingredients because I have a supplement with them. One tablet contains 500 mg of glucosamine and 250 mg of MSM.

    1. Posted by: christopher August 3, 2012, 9:55 AM

      Hi Courtney, thanks for letting me know. The calculator is based off a product called Glycanaid, which is my favorite supplement for dog arthritis.

      The previous table (not sure which page you came from) but was probably Cosequin, which is a much more basic supplement, hence the higher doses required.

      There is in fact a massive variation on these suggested doses anyway. If your tablet is just glucosamine and chondroitin use the higher dose. If it is a multi-ingredient high quality supplement like Glycanaid HA, then use the lower doses.

  7. Posted by: Cuthbert Rumbold October 9, 2011, 7:34 PM

    Your calculator will not accept a weight of 150 lbs, it gives the error “dogs do not weigh this much”. Sure they do! Ever met a Newfoundland, or an Irish Wolfhound, or a Great Dane or (too many to name).

    1. Posted by: christopher October 10, 2011, 6:32 AM

      Ooops Cuthbert, sorry about that. I will get the programmer guy to fix it :)


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